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My CartCAS：147127-20-6
Molecular Formula：C9H14N5O4P
Molecular Weight：287.21
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 147127-20-6 |
| Name | Gtenofovir |
| Molecular Formula | C9H14N5O4P |
| Molecular Weight | 287.21 |
| Solubility | Soluble in Water/DMSO ≥5mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 604-571-2 |
| MDL | MFCD00943794 |
| SMILES | C[C@@H](OCP(O)(O)=O)CN1C=NC2=C(N)N=CN=C12 |
| Target Point | HIV;HBV |
| Passage | Anti-infection |
| Background | Tenofovir is a nucleotide reverse transcriptase inhibitor. |
| Biological Activity | Tenofovir 是一种用于治疗艾滋病毒和慢性乙型肝炎的核苷酸逆转录酶抑制剂。[1-4] |
| Data Literature Source | [1]. Murphy RA，et al. Establishment of HK-2 Cells as a Relevant Model to Study Tenofovir-Induced Cytotoxicity. Int J Mol Sci. 2017 Mar 1;18(3). [2]. Musumeci G，et al. M48U1 and Tenofovir combination synergistically inhibits HIV infection in activated PBMCs and human cervicovaginal histocultures. Sci Rep. 2017 Feb 1;7:41018. [3]. Wahl A，et al. Predicting HIV Pre-exposure Prophylaxis Efficacy for Women using a Preclinical Pharmacokinetic-Pharmacodynamic In Vivo Model. Sci Rep. 2017 Feb 1;7:41098. [4]. Menne S，Cote PJ，Korba BE，Antiviral effect of oral administration of tenofovir disoproxil fumarate in woodchucks with chronic woodchuck hepatitis virus infection. Antimicrob Agents Chemother. 2005 Jul;49(7):2720-8 |
| Unit | Bottle |
| Specification | 50mg 10mM*1mL in DMSO 10mM*1mL in Water 100mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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