CAS:179324-69-7
Storage:Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:White to off-white Solid
Examples of using this product(for reference only)
In Vitro:
Cell (Human PCa cell lines (PC3, LNCaP, C4-2, and Du145);3-1000ng/mL bortezomib):
To determine the IC50 concentration of bortezomib (Solarbio), 5×103 cells/well were seeded onto 96-well microtiter plates and were treated with different concentrations (3, 6, 12, 25, 50, 100, 200, 400, 800, and 1000ng/mL) of bortezomib and media supplemented with 5% fetal bovine serum. The CCK-8 assay was then performed to determine the 50% cell proliferation inhibition rate.
Reference:
Fu Z, Lu C, Zhang C, Qiao B. PSMA5 promotes the tumorigenic process of prostate cancer and is related to bortezomib resistance. Anticancer Drugs. 2019 Aug;30(7):e0773. doi: 10.1097/CAD.0000000000000773. PMID: 30807553.