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My CartCAS：131707-23-8
Molecular Formula：C22H25BrN2O3S·HCl
Molecular Weight：513.88
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to yellow Solid
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| CAS | 131707-23-8 |
| Name | Arbidol Hydrochloride |
| Molecular Formula | C22H25BrN2O3S·HCl |
| Molecular Weight | 513.88 |
| Solubility | Soluble in DMSO ≥10mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 680-680-9 |
| MDL | MFCD00344795 |
| SMILES | Cl.CCOC(=O)C1=C(CSC2=CC=CC=C2)N(C)C2=C1C(CN(C)C)=C(O)C(Br)=C2 |
| InChIKey | OMZHXQXQJGCSKN-UHFFFAOYSA-N |
| InChI | InChI=1S/C22H25BrN2O3S.ClH/c1-5-28-22(27)20-18(13-29-14-9-7-6-8-10-14)25(4)17-11-16(23)21(26)15(19(17)20)12-24(2)3;/h6-11,26H,5,12-13H2,1-4H3;1H |
| PubChem CID | 9958103 |
| Target Point | Influenza Virus |
| Passage | Anti-infection |
| Background | It is a broad-spectrum antiviral compound that inhibits the entry of packaged viruses into cells by blocking the fusion of the virus with the host cell. |
| Biological Activity | Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells[1][2].Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity[3]. |
| Data Literature Source | [1]. Boriskin YS，et al. Arbidol: a broad-spectrum antiviral compound that blocks viral fusion. Curr Med Chem. 2008;15(10):997-1005. [2]. Liu Q，et al. Antiviral and anti-inflammatory activity of arbidol hydrochloride in influenza A (H1N1) virus infection. Acta Pharmacol Sin. 2013;34(8):1075-1083. [3]. Wang X，et al. The anti-influenza virus drug，arbidol is an efficient inhibitor of SARS-CoV-2 in vitro. Cell Discov. 2020;6:28. Published 2020 May 2. |
| Unit | Bottle |
| Specification | 50mg 100mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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