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Your Position: Home > Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Paroxetine Hydrochloride
Paroxetine Hydrochloride

CAS:78246-49-8

Appearance:White to off-white solid

Storage:Powder : -20℃, 2 years;In solvent(mother liquid): -20℃, 1 month; -80℃, 6 months

Purity:HPLC≥98%

   Manual Download
Paroxetine Hydrochloride
Cat.No：
IP1710
Brand：
Solarbio
SKU Tongzhou Beijing Haidian Beijing Wuhan Guangzhou
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Product Information Related Products Related Paper COA Technical Q&A


Examples of using this product（for reference only）

In Vivo:

Rat（Five-week-old male Sprague-Dawley rats，1.8 mg/kg/day Paroxetine，Gavage）:

All rats were kept under a 12 h light/dark cycle at a constant temperature and humidity with ad libitum access to food and water. Rats were allowed to acclimate to housing conditions for a week prior to further treatments. After acclimation, rats were treated with CUMS once a day and lasted for 7 weeks. From 4th to 7th week of CUMS, rats were administrated to L. casei (8×108 CFU/kg/day), paroxetine (1.8 mg/kg/day, a well-known antidepressant purchased from Beijing Solarbio Science &Technology Co.,Ltd., Beijing, China), or equal volume of normal saline by gavage 1 h before they were treated with CUMS, designated L. casei group, positive control group, and CUMS group, respectively. Each rat treated with CUMS was housed separately. Rats only with gavage administration of normal saline without CUMS treatment were used as normal control, and every 5 rats were housed together.

Reference：

Gu F, Wu Y, Liu Y, Dou M, Jiang Y, Liang H . Lactobacillus casei improves depression-like behavior in chronic unpredictable mild stress-induced rats by the BDNF-TrkB signal pathway and the intestinal microbiota. Food Funct. 2020 Jul 1;11(7):6148-6157. doi: 10.1039/d0fo00373e. Epub 2020 Jun 24. PMID: 32578646.

Remark：
These protocols are for reference only. Solarbio does not independently validate these methods.

Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Experimental Images
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Gu F , et al. Food Funct. 2020 Jul 1;11(7):6148-6157.
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