English Name |
Anti-GSTA4 Polyclonal Antibody |
Chinese Name |
谷胱甘肽S-转移酶A4抗体 |
Target |
GSTA4 |
Synonym |
DKFZp686D21185, Glutathione S alkyltransferase A4, Glutathione S aralkyltransferase A4, Glutathione S aryltransferase A4, Glutathione S transferase A4 4, Glutathione S transferase A4, Glutathione S transferase alpha 4, Glutathione S-transferase A4, Glutathione S-transferase A4-4, Glutathione transferase A4 4, GST class alpha member 4, GST class-alpha member 4, GSTA4 4, GSTA4, GSTA4_HUMAN, GTA4, |
Backgroud |
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis. |
Swiss Prot |
O15217 |
Gene ID |
2941 |
Subcellular Localization |
Cytoplasm |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
15/26kDa |
Dilution Ratio |
IHC 1:50-200. |
Immunogen |
Recombinant protein of human GSTA4 |
Public Immunogen Range |
1-222aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human |
Application |
IHC |
Specification |
50ul 100ul |