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Cholic acid

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Cat.No：IC1100 Solarbio

CAS：81-25-4

Molecular Formula：C₂₄H₄₀O₅

Molecular Weight：408.57

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：UV≥98%

Appearance：White to off-white Solid

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Product Information

CAS	81-25-4
Name	Cholic acid
Molecular Formula	C₂₄H₄₀O₅
Molecular Weight	408.57
Solubility	Soluble in DMSO ≥50mg/mL
Purity	UV≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 201-337-8
MDL	MFCD00003672
SMILES	C[C@H](CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@@]21C
Target Point	Others
Passage	Others
Background	Cholic acid is the major bile acid produced in the liver, usually conjugated with glycine or taurine, to aid in fat absorption and cholesterol excretion.
Biological Activity	Cholic acid 是肝脏中产生的主要胆汁酸，通常与甘氨酸或牛磺酸缀合，有助于脂肪吸收和胆固醇排泄。[1-2]
Data Literature Source	[1]. Li Y，et al. Mechanism of hepatic targeting via oral administration of DSPE-PEG-Cholic acid-modified nanoliposomes. Int J Nanomedicine. 2017 Feb 28;12:1673-1684. [2]. Pan X，et al. Cholic acid Feeding Leads to Increased CYP2D6 Expression in CYP2D6-Humanized Mice. Drug Metab Dispos. 2017 Apr;45(4):346-352.
Unit	Bottle
Specification	100mg 10mM*1mL in DMSO 500mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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