Sodium Carboxymethyl Cellulose
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Cat.No：IS9000 Solarbio
CAS：9004-32-4
Storage：Powder:2-8℃，2 years
Purity：Viscosity：800-1200mPa.s
Appearance：White to yellow Solid
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Endocrinology & Hormones
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HIF
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Oscillating Mixing & Stirring & Dispersing Instrument
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> Small Molecule Compounds > Cosolvent & Solubilizer > Sodium Carboxymethyl Cellulose
Product Information
| CAS | 9004-32-4 |
| Name | Sodium Carboxymethyl Cellulose |
| Molecular Formula | No data available |
| Solubility | Soluble in Water ≥10mg/mL |
| Purity | Viscosity：800-1200mPa.s |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years |
| EC | EINECS 900-432-4 |
| MDL | MFCD00081472 |
| Background | It is the sodium salt of cellulose carboxymethyl ether, commonly used as a viscous agent, paste and blocking agent. |
| Unit | Bottle |
| Specification | 5g |
Examples of using this product（for reference only）
In Vivo：
Mice（Eight-week-old male DBA/2J mice，0.5% Na-CMC，Gavage）:
The mice were randomly divided into six groups (n = 6): normal mice group (NC); diabetic mice group (DM); Fer-1 intraperitoneal injected diabetic mice group (Fer-1); 1% dimethyl sulfoxide (DMSO) intraperitoneal injected diabetic mice group (vehicle-P); fenofibrate intragastric administrated diabetic mice group (Fn); 0.5% sodium carboxymethyl cellulose (Na-CMC; Solarbio,Beijing, China) intragastric administrated diabetic mice group (vehicleG). During the duration of 12-week treatment, the diabetic mice in the Fn and vehicle-G groups received intragastric treatment of fenofibrate (100 mg/kg, dissolved in 0.5% Na-CMC) and 0.5% Na-CMC every day, respectively.
Reference：
Li S, Zheng L, Zhang J, Liu X, Wu Z. Inhibition of ferroptosis by up-regulating Nrf2 delayed the progression of diabetic nephropathy. Free Radic Biol Med. 2021 Jan;162:435-449. doi: 10.1016/j.freeradbiomed.2020.10.323. Epub 2020 Nov 2. PMID: 33152439.
Mice(0.5% sodium carboxymethyl cellulose, Oral):
We fully dissolved Dioscin in 0.5% sodium carboxymethyl cellulose (CMC-Na, IS9000, Solarbio) solution in distilled water for In Vivo experiments, and we fully dissolved Dioscin in 0.01% dimethyl sulfoxide (DMSO, D8371, Solarbio) for In Vitro experiments.
Reference：
Shi L, Zhang P, Jin R, Chen X, Dong L, Chen W. Dioscin ameliorates inflammatory bowel disease by up-regulating miR-125a-5p to regulate macrophage polarization. J Clin Lab Anal. 2022 Jun;36(6):e24455. doi: 10.1002/jcla.24455. Epub 2022 May 7. PMID: 35524480; PMCID: PMC9169194.
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Experimental Images
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