English Name |
Anti-MXI1 Polyclonal Antibody |
Chinese Name |
MAX相互作用蛋白1抗体 |
Target |
MXI1 |
Synonym |
bHLHc11, Class C basic helix-loop-helix protein 11, MAD 2, MAD2, MAX dimerization protein 2, MAX interacting protein 1, Max interactor 1, Max related transcription factor, MAX-interacting protein 1, MGC43220, MXD 2, MXD2, MXI 1, MXI, mxi1, MXI1 protein, MXI1_HUMAN, Protein MXI1 |
Backgroud |
Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally |
Swiss Prot |
P50539 |
Gene ID |
4601 |
Subcellular Localization |
Nucleus Cytoplasm |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
22/26/33kDa |
Dilution Ratio |
WB 1:1000-3000. |
Immunogen |
Recombinant protein of human MXI1 |
Public Immunogen Range |
1-228aa |
Purification Method |
Octanoic acid-ammonium sulfate precipitation |
Storage Buffer |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat Mouse |
Application |
WB |
Specification |
50ul 100ul |