English Name |
Anti-NOD1 Polyclonal Antibody |
Chinese Name |
核苷酸结合寡聚化结构域2抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:500-2000. IHC 1:50-200. |
Target |
NOD1 |
Synonyms |
CARD 4, CARD4, Caspase recruitment domain 4, Caspase recruitment domain containing protein 4, Caspase recruitment domain family member 4, Caspase recruitment domain protein 4, Caspase recruitment domain-containing protein 4, CLR 7.1, CLR7.1, NLR family CARD domain containing 1, NLRC 1, NLRC1, NOD 1, Nod1, NOD1 protein, NOD1_HUMAN, Nucleotide binding oligomerization domain containing 1, Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 1, Nucleotide-binding oligomerization domain-containing protein 1, Protein Nod1 |
Background |
This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. |
Swiss Prot |
Q9Y239 |
Gene ID |
10392 |
Subcellular Location |
Apical cell membrane Basolateral cell membrane Cell membrane Cytoplasm |
Immunogen |
Recombinant protein of human NOD1 |
Public Immunogen Range |
1-270aa |
Calculated MW |
27/107kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 0.03% Proclin300,50% glycerol,pH7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Unit |
Piece |
Specification |
50ul 100ul |