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My CartReactivity：Human,Mouse,Rat
Application：WB,IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：10188
Host：Rabbit
Qty：
Size：
| Name | Anti-TNK2 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:500-2000. IHC 1:50-200. |
| Target | TNK2 |
| Background | This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. |
| Swiss Prot | Q07912 |
| Gene ID | 10188 |
| Subcellular Location | Cell junction Cell membrane Cytoplasmic side Cytoplasmic vesicle Cytoplasmic vesicle membrane Endosome Membrane Nucleus Peripheral membrane protein Adherens junction Clathrin-coated pit Cathrin-coated vesicle |
| Immunogen | Recombinant protein of human TNK2 |
| Public Immunogen Range | 390-580aa |
| Calculated MW | 60/114/119kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.03% Proclin300，50% glycerol，pH7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Human Mouse Rat |
| Application | IHC WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with TNK2 antibody diluted at 1:1000;Lane: SW620 HT-29 MCF7 Raji.
Immunohistochemistry of paraffin-embedded human liver with TNK2 antibody diluted at 1:100.
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