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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Protein Tyrosine Kinase/PTK > WH-4-023CAS：837422-57-8
Molecular Formula：C32H36N6O4
Molecular Weight：568.67
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 837422-57-8 |
| Name | WH-4-023 |
| Molecular Formula | C32H36N6O4 |
| Molecular Weight | 568.67 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD28138072 |
| SMILES | O=C(OC1=C(C)C=CC=C1C)N(C2=CC=C(OC)C=C2OC)C3=NC(NC4=CC=C(N5CCN(C)CC5)C=C4)=NC=C3 |
| Target Point | LCK;Src |
| Passage | Protein Tyrosine Kinase/RTK |
| Background | WH-4-023 is a potent and selective Lck/Src inhibitor. |
| Biological Activity | WH-4-023 是一种有效的选择性的 Lck/Src 抑制剂，IC50 分别为 2 nM/6 nM，对p38α 和 KDR作用效果稍弱。[1] |
| Data Literature Source | [1]. Martin MW，et al. Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis，SAR，and in vivo antiinflammatory activity. J Med Chem. 2006 Aug 10;49(16):4981-91 |
| Unit | Bottle |
| Specification | 5mg 10mg 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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