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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Protein Tyrosine Kinase/PTK > BAY 61-3606 dihydrochlorideCAS：648903-57-5
Molecular Formula：C20H20Cl2N6O3
Molecular Weight：463.32
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Off-white to yellow Solid
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| CAS | 648903-57-5 |
| Name | BAY 61-3606 dihydrochloride |
| Molecular Formula | C20H20Cl2N6O3 |
| Molecular Weight | 463.32 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Off-white to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD08276916 |
| SMILES | O=C(N)C1=CC=CN=C1NC2=NC(C3=CC=C(C(OC)=C3)OC)=CC4=NC=CN24.[H]Cl.[H]Cl |
| Target Point | Syk |
| Passage | Protein Tyrosine Kinase/RTK |
| Background | BAY-61-3606 is a potent and selective inhibitor of Syk kinase. |
| Biological Activity | BAY-61-3606是一种有效的、选择性的Syk激酶抑制剂，Ki为7.5 nM。BAY-61-3606可诱导细胞周期阻滞和凋亡。[1-2] |
| Data Literature Source | [1] Yamamoto N，et al. J Pharmacol Exp Ther. 2003，306(3):1174-81. [2] Kim SY，et al. PLoS One. 2015，10(12):e0146073. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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