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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Protein Tyrosine Kinase/PTK > PRT062607 HydrochlorideCAS：1370261-97-4
Molecular Formula：C19H24ClN9O
Molecular Weight：429.91
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
Qty：
Size：
| CAS | 1370261-97-4 |
| Name | PRT062607 Hydrochloride |
| Molecular Formula | C19H24ClN9O |
| Molecular Weight | 429.91 |
| Solubility | Soluble in Water/DMSO |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD25976708 |
| SMILES | NC(C1=CN=C(N[C@H]2[C@@H](N)CCCC2)N=C1NC3=CC=CC(N4N=CC=N4)=C3)=O.[H]Cl |
| Target Point | Syk |
| Passage | Protein Tyrosine Kinase/RTK |
| Background | PRT062607 hydrochloride is a potent Syk inhibitor. |
| Biological Activity | PRT062607 hydrochloride 是一种有效的纯化的 Syk 抑制剂，IC50 为 1-2 nM。[1] |
| IC50 | 1nM(Syk)，81nM(Fgr)，88nM(MLK1)，123nM(Yes)[1] |
| Data Literature Source | [1]. Coffey G，et al. Specific inhibition of spleen tyrosine kinase suppresses leukocyte immune function and inflammation in animal models of rheumatoid arthritis. J Pharmacol Exp Ther. 2012 Feb;340(2):350-9. |
| Unit | Bottle |
| Specification | 5mg 10mM*1mL in DMSO 10mM*1mL in Water 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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