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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > PepstatinCAS：26305-03-3
Molecular Formula：C34H63N5O9
Molecular Weight：685.89
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥75%
Appearance：White to off-white Solid
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| CAS | 26305-03-3 |
| Name | Pepstatin |
| Molecular Formula | C34H63N5O9 |
| Molecular Weight | 685.89 |
| Solubility | Soluble in Water ≥10mg/mL;Soluble in DMSO ≥1mg/mL(Need ultrasonic or Water bath) |
| Purity | HPLC≥75% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 247-600-0 |
| MDL | MFCD00060740 |
| SMILES | CC(C[C@H](NC([C@@H](NC([C@@H](NC(CC(C)C)=O)C(C)C)=O)C(C)C)=O)[C@@H](O)CC(N[C@@H](C)C(N[C@@H](CC(C)C)[C@@H](O)CC(O)=O)=O)=O)C |
| InChIKey | FAXGPCHRFPCXOO-LXTPJMTPSA-N |
| InChI | InChI=1S/C34H63N5O9/c1-17(2)12-23(37-33(47)31(21(9)10)39-34(48)30(20(7)8)38-27(42)14-19(5)6)25(40)15-28(43)35-22(11)32(46)36-24(13-18(3)4)26(41)16-29(44)45/h17-26,30-31,40-41H,12-16H2,1-11H3,(H,35,43)(H,36,46)(H,37,47)(H,38,42)(H,39,48)(H,44,45)/t22-,23-,24-,25-,26-,30-,31-/m0/s1 |
| PubChem CID | 5478883 |
| Target Point | Proteasome |
| Passage | Metabolic Enzyme&Protease |
| Background | Pepstatin is a specific inhibitor of aspartic proteases. |
| Biological Activity | Pepstatin 是一种特异性的天冬氨酸蛋白酶 (aspartic proteases) 抑制剂，能够抑制 hemoglobin-pepsin，hemoglobin-proctase，casein-pepsin，casein-proctase，casein-acid protease 和 hemoglobin-acid protease 的活性，IC50 值分别为 4.5 nM，6.2 nM，150 nM，290 nM，520 nM 和 260 nM。[1] |
| Data Literature Source | [1]. Umezawa H，et al. Pepstatin，a new pepsin inhibitor produced by Actinomycetes. J Antibiot (Tokyo). 1970 May;23(5):259-62 |
| Unit | Bottle |
| Specification | 5mg 10mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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