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My CartReactivity：Human,Rat,Mouse
Application：IF,IHC,WB
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：3553
Host：Rabbit
Qty：
Size：
| Name | Anti-IL1B Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:2000-5000. IHC 1:25-100. IF 1:50-200. |
| Target | IL1B |
| Background | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. |
| Swiss Prot | P01584 |
| Gene ID | 3553 |
| Subcellular Location | Cytoplasm |
| Immunogen | Recombinant protein of human IL1B |
| Public Immunogen Range | 1-269aa |
| Calculated MW | 31kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Rat Mouse |
| Application | WB IHC IF |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with IL1B antibody diluted at 1:4000;Lane: Mouse liver,Rat liver.
Immunohistochemistry of paraffin-embedded Human stomach cancer with IL1B antibody diluted at 1:50.
Immunofluorescence analysis of SH-SY5Y cells using IL1B antibody diluted at 1:100.
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Click to check >>Author：Kun Shi, Yan Wang, Yangxin Xiao, Jiyuan Tu, Zhongshi Zhou, Guosheng Cao, Yanju Liu
IF：5.9880
Publish_to：Frontiers in Pharmacology
PMID：37168993
Exercise reduces hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice via its effects against inflammation and oxidative stress
Click to check >>Author：Pei Zuowei, Ji Jun, Gao Yanyan, Wang Heshuang, Wu Yuanyuan, Yang Jin, Yang Qin, Zhang Li
IF：4.6000
Publish_to：Scientific Reports
PMID：37277452
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