English Name |
Anti-CD47 Polyclonal Antibody |
Chinese Name |
整合素相关蛋白CD47抗体 |
Target |
CD47 |
Synonym |
Antigenic surface determinant protein OA3, CD 47, CD47, CD47 antigen, CD47 glycoprotein, CD47 molecule, CD47_HUMAN, IAP, Integrin Associated Protein, Integrin associated signal transducer, Integrin-associated protein, Leukocyte surface antigen CD47, MER 6, MER6, OA 3, OA3, Protein MER6, Rh related antigen |
Backgroud |
Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. |
Swiss Prot |
Q08722 |
Gene ID |
961 |
Subcellular Localization |
Cell membrane Cytoplasm |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
35/34/33/32kDa |
Dilution Ratio |
WB 1:1000-3000. IF 1:50-200. |
Immunogen |
A synthetic peptide of human CD47 |
Public Immunogen Range |
60-110/323aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat Mouse |
Application |
WB IF |
Specification |
50ul 100ul |