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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Autophagy > IITZ-01CAS：1807988-47-1
Molecular Formula：C26H23FN8O
Molecular Weight：482.51
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1807988-47-1 |
| Name | IITZ-01 |
| Molecular Formula | C26H23FN8O |
| Molecular Weight | 482.51 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | FC1=CC=C(NC2=NC(N3CCOCC3)=NC(NC4=CC=C(C5=NC6=CC=CC=C6N5)C=C4)=N2)C=C1 |
| InChIKey | XGEDDGLPNSLBFE-UHFFFAOYSA-N |
| InChI | InChI=1S/C26H23FN8O/c27-18-7-11-20(12-8-18)29-25-32-24(33-26(34-25)35-13-15-36-16-14-35)28-19-9-5-17(6-10-19)23-30-21-3-1-2-4-22(21)31-23/h1-12H,13-16H2,(H,30,31)(H2,28,29,32,33,34) |
| PubChem CID | 134817273 |
| Target Point | Autophagy |
| Passage | Autophagy |
| Background | LRRK2-IN-1 is a potent and selective LRRK2 inhibitor. |
| Biological Activity | IITZ-01是一种有效的自噬（autophagy）抑制剂，可增强自噬体的积累，但通过破坏溶酶体功能抑制自噬体的退化。[1] |
| Data Literature Source | [1] Guntuku L，et al. Oncogene. 2018，doi: 10.1038/s41388-018-0446-2. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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