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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Autophagy > CA-5fCAS：1370032-19-1
Molecular Formula：C24H24N2O3
Molecular Weight：388.46
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 1370032-19-1 |
| Name | CA-5f |
| Molecular Formula | C24H24N2O3 |
| Molecular Weight | 388.46 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD31813689 |
| SMILES | O=C(/C(CN(C)C/1)=C/C2=CNC3=C2C=CC=C3)C1=C\C4=CC=C(OC)C(OC)=C4 |
| Target Point | Autophagy |
| Passage | Autophagy |
| Background | CA-5f is a potent late-stage macroautophagy/autophagy inhibitor that acts by inhibiting autophagosome lysosome fusion. CA-5f can increase LC3B-II (a marker that monitors autophagy) and SQSTM1 protein levels, promoting ROS production. |
| Biological Activity | CA-5f是一种有效的自噬晚期（late-stage autophagy）抑制剂，通过抑制自噬体-溶酶体融合发挥作用。[1] |
| Data Literature Source | [1] Zhang L，et al. Autophagy. 2019，15(3):391-406. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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