{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > BMS-265246CAS：582315-72-8
Molecular Formula：C18H17F2N3O2
Molecular Weight：345.34
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
Qty：
Size：
| CAS | 582315-72-8 |
| Name | BMS-265246 |
| Molecular Formula | C18H17F2N3O2 |
| Molecular Weight | 345.34 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD22420825 |
| SMILES | CC1=CC(F)=C(C(C2=CN=C(NN=C3)C3=C2OCCCC)=O)C(F)=C1 |
| Target Point | CDK1/CyclinB，CDK2/CyclinE，CDK4/CyclinD |
| Passage | Cell Cycle |
| Background | BMS-265246 is a CDK1/2 inhibitor. |
| Biological Activity | BMS-265246是一种有效的选择性CDK1/2抑制剂，无细胞试验中IC50为6 nM/9 nM。作用于CDK1/2 比作用于CDK4选择性高25倍。[1] |
| IC50 | CDK1/CyclinB : 6nM(Cell-free assay);CDK2/CyclinE: 9nM(Cell-free assay);CDK4/CyclinD: 230nM(Cell-free assay) [1] |
| Data Literature Source | [1] Misra RN，et al. Bioorg Med Chem Lett. 2003，13(14)，2405-2408. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
