English Name |
Anti-CNOT9 Polyclonal Antibody |
Chinese Name |
细胞分化蛋白质RCD1抗体 |
Target |
CNOT9 |
Synonym |
CAF40, CCR4-NOT transcription complex subunit 9, Cell differentiation protein RCD1 homolog, CNOT9, CT129, Homo sapiens protein involved in sexual development complete cds, Rcd 1, Rcd-1, Rcd1 (required for cell differentiation, S.pombe) homolog 1, RCD1, RCD1 required for cell differentiation1 homolog, RCD1 required for cell differentiation1 homolog (S. pombe), RCD1+, RCD1_HUMAN, rqcd1 |
Backgroud |
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all. |
Swiss Prot |
Q92600 |
Gene ID |
9125 |
Subcellular Localization |
Cytoplasm |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
29/34/37kDa |
Dilution Ratio |
IHC 1:25-100. |
Immunogen |
A synthetic peptide of human CNOT9 |
Public Immunogen Range |
30-80/299aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat Mouse |
Application |
IHC |
Specification |
50ul 100ul |