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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > DNA Damage & DNA Repai > ScriptaidCAS：287383-59-9
Molecular Formula：C18H18N2O4
Molecular Weight：326.35
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 287383-59-9 |
| Name | Scriptaid |
| Molecular Formula | C18H18N2O4 |
| Molecular Weight | 326.35 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00386477 |
| SMILES | O=C(NO)CCCCCN(C(C1=CC=CC2=CC=CC3=C12)=O)C3=O |
| InChIKey | JTDYUFSDZATMKU-UHFFFAOYSA-N |
| InChI | InChI=1S/C18H18N2O4/c21-15(19-24)10-2-1-3-11-20-17(22)13-8-4-6-12-7-5-9-14(16(12)13)18(20)23/h4-9,24H,1-3,10-11H2,(H,19,21) |
| PubChem CID | 5186 |
| Target Point | HDAC |
| Passage | DNA Damage/DNA Repair;Epigenetics;NF-κB |
| Background | Scriptaid is an HDAC inhibitor. |
| Biological Activity | Scriptaid 是一种组蛋白去乙酰化酶 (HDAC) 抑制剂，可用于癌症研究。[1] |
| Data Literature Source | [1]. Keen JC，et al. A novel histone deacetylase inhibitor，scriptaid，enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine. Breast Cancer Res Treat. 2003 Oct;81(3):177-86. [2]. Strobl JS，et al. Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro. J Parasitol. 2007 Jun;93(3):694-700. [3]. Janaki Ramaiah M，et al. Scriptaid cause histone deacetylase inhibition and cell cycle arrest in HeLa cancer cells: A study on structural and functional aspects. Gene. 2017 Sep 5;627:379-386 |
| Unit | Bottle |
| Specification | 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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