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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > DNA Damage & DNA Repai > AZD-0156CAS：1821428-35-6
Molecular Formula：C26H31N5O3
Molecular Weight：461.56
Storage：Powder:-20℃，2 years
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1821428-35-6 |
| Name | AZD-0156 |
| Molecular Formula | C26H31N5O3 |
| Molecular Weight | 461.56 |
| Solubility | Soluble in DMSO ≥0.5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years |
| MDL | MFCD30470661 |
| SMILES | O=C(N1C2CCOCC2)N(C)C3=C1C4=CC(C5=CC=C(OCCCN(C)C)N=C5)=CC=C4N=C3 |
| Target Point | ATM/ATR |
| Passage | DNA Damage/DNA Repair; PI3K/Akt/mTOR |
| Background | AZD0156 is a potent and selective ATM kinase inhibitor |
| Biological Activity | AZD0156 是有效的、选择性的ATM激酶抑制剂，具有潜在的化疗/辐射增敏和抗肿瘤活性。AZD0156 可防止DNA损伤检查点激活，破坏DNA损伤修复，诱导肿瘤细胞凋亡，并导致过表达ATM的肿瘤细胞死亡。[1] |
| Data Literature Source | [1] Kurt G. Pike. Cancer Res. 2016，76(14 Suppl):Abstract nr 485 |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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