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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > JAK/STAT > SH-4-54CAS：1456632-40-8
Molecular Formula：C29H27F5N2O5S
Molecular Weight：610.59
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to yellow Solid
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| CAS | 1456632-40-8 |
| Name | SH-4-54 |
| Molecular Formula | C29H27F5N2O5S |
| Molecular Weight | 610.59 |
| Solubility | Soluble in DMSO ≥10mg/mL |
| Purity | ≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD28143917 |
| SMILES | O=C(O)C1=CC=C(N(CC2=CC=C(C3CCCCC3)C=C2)C(CN(C)S(=O)(C4=C(F)C(F)=C(F)C(F)=C4F)=O)=O)C=C1 |
| Target Point | STAT |
| Passage | JAK/STAT Signaling |
| Background | SH-4-54 is a potent, unphosphorylated STAT inhibitor. |
| Biological Activity | SH-4-54 是一种有效的，未磷酸化的 STAT 抑制剂，其对 STAT3 和 STAT5 的 KD 值分别为 300，464 nM。[1] |
| Data Literature Source | [1]. Haftchenary S，et al. Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma. ACS Med Chem Lett. 2013 Sep 8;4(11):1102-1107 |
| Unit | Bottle |
| Specification | 2mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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