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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > JAK/STAT > StatticCAS：19983-44-9
Molecular Formula：C8H5NO4S
Molecular Weight：211.19
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 19983-44-9 |
| Name | Stattic |
| Molecular Formula | C8H5NO4S |
| Molecular Weight | 211.19 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00173799 |
| SMILES | O=[N+](C1=CC=C(C=CS2(=O)=O)C2=C1)[O-] |
| Target Point | STAT3 |
| Passage | JAK/STAT Signaling |
| Background | Stattic is a potent inhibitor of STAT3 activation and dimerization. |
| Biological Activity | Stattic是有效的 STAT3 活化和二聚化的抑制剂。[1-2] |
| Data Literature Source | [1]. Lin L，et al. STAT3 as a potential therapeutic target in ALDH+ and CD44+/CD24+ stem cell-like pancreatic cancer cells. Int J Oncol. 2016 Oct 12. [2]. Cho YS，et al. Inhibition of STAT3 phosphorylation by sulforaphane reduces adhesion molecule expression in vascular endothelial cell. Can J Physiol Pharmacol. 2015 Nov 18:1-7 |
| Unit | Bottle |
| Specification | 10mg 10mM*1mL in DMSO 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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