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My CartReactivity：Human,Monkey,Rat,Mouse
Application：WB,IP,IHC
Clone Type：Monoclonal antibody
Storage：Store at -20℃. Do not aliquot the antibody.
Gene ID：5781
Host：Rabbit
Qty：
Size：
| Name | Anti-SHP-2 Monoclonal Antibody |
| Host | Rabbit |
| Clone Type | Monoclonal antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:500-2000. IHC 1:50. IP 1:50. |
| Target | SHP-2 |
| Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. |
| Swiss Prot | Q06124 |
| Gene ID | 5781 |
| Subcellular Location | Cytoplasm |
| Immunogen | A synthesized peptide derived from human SHP-2 |
| Calculated MW | 53/68kDa |
| Purification Method | Affinity purification |
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5)，150 mM NaCl，100 μg/ml BSA，50% glycerol and less than 0.02% sodium azide. |
| Storage | Store at -20℃. Do not aliquot the antibody. |
| Unit | Piece |
| Specification | 100ul |
| Reactivity | Human Monkey Rat Mouse |
| Application | IHC WB IP |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with SHP-2 antibody diluted at 1:1000;Lane: HeLa,293,COS,NIH/3T3
Immunohistochemistry of paraffin-embedded Human breast cancer with SHP-2 antibody diluted at 1:50
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