Gene Name |
ATP6V1D |
English Name |
V-type proton ATPase subunit D, V-ATPase subunit D |
Chinese Name |
6型质子ATPase亚单位D |
Uniprot |
Q9Y5K8 |
GeneID |
51382 |
Predicted Cross Reactivity |
Human Mouse (Bovine Rabbit Gorilla) |
氨基酸大小 |
28kDa |
表达氨基酸 |
1-247aa |
Background |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles.V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain.The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits.The V1 domain contains the ATP catalytic site.The V0 domain consists of five different subunits: a, c, c', c, and d.Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants.This gene encodes the V1 domain D subunit protein. |
Application |
Immunology research |
Source |
E.coli |
Purification |
NI-NTA affinity purification |
Formulation |
Lyophilized from a 0.2 μm filtered solution of Urea, Tris-HCl, PH8.0. |
Delivery Condition |
The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage |
Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
Reconstitution |
Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Purity |
Purity≥85% as determined by reducing SDS-PAGE. |
Bioactive |
Not tested. |
Tag information |
With a 6His tag at the N-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |