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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > JAK/STAT > BP-1-102CAS：1334493-07-0
Molecular Formula：C29H27F5N2O6S
Molecular Weight：626.59
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1334493-07-0 |
| Name | BP-1-102 |
| Molecular Formula | C29H27F5N2O6S |
| Molecular Weight | 626.59 |
| Solubility | Soluble in DMSO ≥5mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD29477477 |
| SMILES | O=C(O)C1=CC=C(N(CC2=CC=C(C3CCCCC3)C=C2)C(CN(C)S(=O)(C4=C(F)C(F)=C(F)C(F)=C4F)=O)=O)C=C1O |
| Target Point | STAT3 |
| Passage | JAK/STAT Signaling |
| Background | BP-1-102 is a potent and selective STAT3 inhibitor |
| Biological Activity | BP-1-102是有效的、具有口服生物活性的、选择性STAT3抑制剂，与STAT3结合亲和力Kd为504 nM.在4-6.8 μM时，抑制Stat3与pTyr肽段的相互作用和STAT3的激活。[1] |
| IC50 | STAT3: 504nM(Kd) [1] |
| Data Literature Source | [1] Zhang X，et al. Proc Natl Acad Sci U S A. 2012，109(24):9623- |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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