CAS:906673-24-3
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:White to off-white Solid
是一种有效的,选择性的PDE4抑制剂,具有广谱的抗炎活性。通过抑制PDE4起作用,从而抑制了诸如TNFα,IL-12,IL-23等细胞因子的释放。
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CrisaboroleCAS:906673-24-3
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:White to off-white Solid
CAS | 906673-24-3 |
Chinese Name | 克洛硼罗 |
English Name | Crisaborole |
Synonyms | PF-06930164;AN-2728 |
Molecular Formula | C14H10BNO3 |
Molecular Weight | 251.05 |
Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
Purity | ≥98% |
Appearance | White to off-white Solid |
Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
MDL | MFCD17169940 |
SMILES | B1(C2=C(CO1)C=C(C=C2)OC3=CC=C(C=C3)C#N)O |
Target Point | Phosphodiesterase (PDE) |
Passage | Metabolic Enzyme&Protease |
Background | Crisaborole is a potent, selective PDE4 inhibitor with broad-spectrum anti-inflammatory activity. Works by inhibiting PDE4, thereby inhibiting the release of cytokines such as TNFα, IL-12, IL-23. |
Unit | Bottle |
Specification | 5mg 10mg |
是一种有效的,选择性的PDE4抑制剂,具有广谱的抗炎活性。通过抑制PDE4起作用,从而抑制了诸如TNFα,IL-12,IL-23等细胞因子的释放。