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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Apoptosis > DehydrocorydalinCAS：30045-16-0
Molecular Formula：C22H24NO4
Molecular Weight：366.43
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 30045-16-0 |
| Name | Dehydrocorydalin |
| Molecular Formula | C22H24NO4 |
| Molecular Weight | 366.43 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | HPLC≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00887635 |
| SMILES | CC1=C(C=CC(OC)=C2OC)C2=C[N+]3=C1C4=CC(OC)=C(OC)C=C4CC3 |
| InChIKey | RFKQJTRWODZPHF-UHFFFAOYSA-N |
| InChI | InChI=1S/C22H24NO4/c1-13-15-6-7-18(24-2)22(27-5)17(15)12-23-9-8-14-10-19(25-3)20(26-4)11-16(14)21(13)23/h6-7,10-12H,8-9H2,1-5H3/q+1 |
| PubChem CID | 34781 |
| Target Point | Bcl-2 Family; Caspase; PARP; p38 MAPK; Parasite; Autophagy |
| Passage | MAPK |
| Background | It is an alkaloid in the traditional Chinese medicine Corydalis yanhusuo. Regulates Bax, Bcl-2 protein expression; activates caspase-7, caspase-8, and inactivates PARP. |
| Biological Activity | Dehydrocorydaline (13-Methylpalmatine) 是从中药延胡索 Corydalis yanhusuo 中分离得到的一种生物碱。Dehydrocorydaline 调节 Bax，Bcl-2 蛋白表达；激活 caspase-7，caspase-8，并使 PARP 失活。[1-2] |
| Data Literature Source | [1]. Xu Z，et al. Dehydrocorydaline inhibits breast cancer cells proliferation by inducing apoptosis in MCF-7 cells. Am J Chin Med. 2012;40(1):177-85. [2]. Yin ZY，et al. Antinociceptive effects of dehydrocorydaline in mouse models of inflammatory pain involve the opioid receptor and inflammatory cytokines. Sci Rep. 2016 Jun 7;6:27129 |
| Unit | Bottle |
| Specification | 5mg 10mg 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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