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Recombinant Human PGDH(15-PGDH)/HPGD

Cat.No：P01910 Solarbio

Purity：≥95% as determined by reducing SDS-PAGE.

Storage：Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Appearance：Supplied as a 0.2 μm filtered solution of 20mM HEPES,150mM NaCl,pH7.4.

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Product Information

Appearance	Supplied as a 0.2 μm filtered solution of 20mM HEPES,150mM NaCl,pH7.4.
Purity	≥95% as determined by reducing SDS-PAGE.
Storage	Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Background	15-hydroxyprostaglandin dehydrogenase [NAD(+)]，also known as Prostaglandin dehydrogenase 1，15-PGDH，HPGD and PGDH1，belongs to the short-chain dehydrogenases/reductases (SDR) family.HPGD localizes to the cytoplasm and can be found in colon epithelium，existing as a homodimer.HPGD catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4.HPGD is down-regulated by cortisol，dexamethasone and betamethasone，up-regulated by TGFB1.HPGD inhibits in vivo proliferation of colon cancer cells.HPGD is the key enzyme for the inactivation of prostaglandins，and thus regulates processes such as inflammation or proliferation.
Source	Human Cells
Endotoxin	Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
Unit	Piece
Specification	10ug 50ug 500ug 1mg

Cell growth factor

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.

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