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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > OpaganibCAS：915385-81-8
Molecular Formula：C23H25ClN2O
Molecular Weight：380.91
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 915385-81-8 |
| Name | Opaganib |
| Molecular Formula | C23H25ClN2O |
| Molecular Weight | 380.91 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD22666355 |
| SMILES | O=C(C1(C2)CC3(C4=CC=C(Cl)C=C4)CC2CC(C3)C1)NCC5=CC=NC=C5 |
| Target Point | sphingosine kinase-2 (SphK2) |
| Passage | Immunology & Inflammation |
| Background | Opaganib is a selective and competitive inhibitor of sphingosine kinase-2 (SphK2). |
| Biological Activity | Opaganib (ABC294640)是一种口服生物可利用的选择性sphingosine kinase-2 (SphK2)抑制剂，IC50约为 60 μM。[1-4] |
| Data Literature Source | [1] French KJ，et al. J Pharmacol Exp Ther. 2010，333(1)，129-139. [2] Beljanski V，et al. J Pharmacol Exp Ther. 2010，333(2)，454-464. [3] Antoon JW，et al. Endocrinology. 2010，151(11)，5124-5135. [4] Liu Q，et al. PLoS One. 2012，7(7)，e41834. |
| Unit | Bottle |
| Specification | 2mg 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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