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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Epigenetics > SP2509CAS：1423715-09-6
Molecular Formula：C19H20ClN3O5S
Molecular Weight：437.9
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1423715-09-6 |
| Name | SP2509 |
| Molecular Formula | C19H20ClN3O5S |
| Molecular Weight | 437.9 |
| Solubility | Soluble in DMSO ≥5mg/mL;Soluble in Water ＜ 1mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD28348370 |
| SMILES | O=C(N/N=C(C1=CC(Cl)=CC=C1O)C)C2=CC=CC(S(=O)(N3CCOCC3)=O)=C2 |
| Target Point | LSD1 |
| Passage | Epigenetics |
| Background | SP2509 is a selective histone demethylase LSD1 inhibitor. |
| Biological Activity | SP2509 是有效的，选择性的 LSD1 拮抗剂，IC50 值为 13 nM。[1-2] |
| IC50 | 13nM(LSD1)[1] |
| Data Literature Source | [1]. Fiskus W，et al. Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells. Leukemia. 2014 Nov;28(11):2155-64. [2]. Inui K，et al. Stepwise assembly of functional C-terminal REST/NRSF transcriptional repressor complexes as a drug target. Protein Sci. 2017 Feb 20. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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