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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Epigenetics > UNC1999CAS：1431612-23-5
Molecular Formula：C33H43N7O2
Molecular Weight：569.74
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to yellow Solid
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| CAS | 1431612-23-5 |
| Name | UNC1999 |
| Molecular Formula | C33H43N7O2 |
| Molecular Weight | 569.74 |
| Solubility | Soluble in DMSO ≥10mg/mL |
| Purity | ≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD26960958 |
| SMILES | O=C1C(CNC(C2=C(C=NN3C(C)C)C3=CC(C4=CN=C(N5CCN(C(C)C)CC5)C=C4)=C2)=O)=C(CCC)C=C(C)N1 |
| Target Point | EZH1，EZH2 |
| Passage | Epigenetics |
| Background | UNC1999 is a potent EZH2 and EZH1 selective inhibitor. |
| Biological Activity | UNC1999 是一种有效，选择性和SAM-竞争性的 EZH2 和 EZH1 抑制剂，IC50 分别为 10 nM 和 45 nM。[1] |
| Data Literature Source | [1]. Konze KD，et al. An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1. ACS Chem Biol. 2013;8(6):1324-34 |
| Unit | Bottle |
| Specification | 5mg 10mg 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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