| Gene Name |
CHI3L1 |
| Synonyms |
39 a synovial protein;ASRT7;Cartilage glycoprotein 39;CGP-39;CGP39;CH3L1_HUMAN;CHI3L1;chitinase 3 like 1 (cartilage glycoprotein 39);chitinase 3 like 1;Chitinase 3 like protein 1 precursor;chitinase;Chitinase-3-like protein 1;Chondrocyte protein YKL40;GP 39;GP-39;GP39;HC gp39;HCGP 3P;hCGP-39;HCgp39;YKL 40;YKL-40;YKL40;YYL 40; |
| English Name |
Recombinant human CHI3L1 protein |
| Full Name |
Chitinase-3-like protein 1 |
| Chinese Name |
几丁质酶-3样蛋白1 |
| Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
| Purity |
≥85% by SDS-PAGE. |
| Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
| Concentration |
1mg/ml by SDS-PAGE. |
| Swiss Prot |
P36222 |
| Gene ID |
1116 |
| Reactivity |
Human Mouse Rat (Bovine Goat Sheep Pig Orangutan) |
| Molecular Weight |
43kDa |
| Interval Range |
34-383aa |
| Background |
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung. |
| Application |
Immunology research |
| Source |
E.coli |
| Purification Method |
NI-NTA affinity purification |
| Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| Endotoxin |
Not measured |
| Biological Activity |
N0 |
| Lable Information |
With a 6×His tag at the N/C-terminus. |
| Unit |
Piece |
| Specification |
10ug 50ug 100ug 1mg |
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