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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > ClofazimineCAS：2030-63-9
Molecular Formula：C27H22Cl2N4
Molecular Weight：473.4
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
Qty：
Size：
| CAS | 2030-63-9 |
| Name | Clofazimine |
| Molecular Formula | C27H22Cl2N4 |
| Molecular Weight | 473.4 |
| Solubility | Soluble in DMSO ≥1mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 217-980-2 |
| MDL | MFCD00056793 |
| SMILES | CC(/N=C1C(NC2=CC=C(Cl)C=C2)=CC3=NC4=C(C=CC=C4)N(C5=CC=C(Cl)C=C5)C3=C/1)C |
| InChIKey | WDQPAMHFFCXSNU-UHFFFAOYSA-N |
| InChI | InChI=1S/C27H22Cl2N4/c1-17(2)30-24-16-27-25(15-23(24)31-20-11-7-18(28)8-12-20)32-22-5-3-4-6-26(22)33(27)21-13-9-19(29)10-14-21/h3-17,31H,1-2H3 |
| PubChem CID | 2794 |
| Target Point | Others |
| Passage | Immunology & Inflammation |
| Background | Clofazimine is a rhimophenazine dye with antibacterial and anti-inflammatory activity. |
| Biological Activity | Clofazimine(CFM; also known as B663 or Lamprene) was developed initially as an antituberculosis drug (1–3). In the earlier experimental tuberculosis studies with hamster and mouse models, the drug was found to be effective. Subsequently, on the basis of the fact that it concentrates extensively inside macrophages and on the basis of the logic of using an intracellular drug on an intracellular parasite, CFM has been used successfully for the treatment of leprosy. [1] |
| Data Literature Source | [1]. Reddy VM，Nadadhur G，Daneluzzi D，O'Sullivan JF，Gangadharam PR. Antituberculosis activities of clofazimine and its new analogs B4154 and B4157. Antimicrob Agents Chemother. 1996 Mar;40(3):633-36. |
| Unit | Bottle |
| Specification | 250mg 500mg 1g |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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