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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > ABX-1431CAS：1446817-84-0
Molecular Formula：C20H22F9N3O2
Molecular Weight：507.39
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to yellow Solid
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| CAS | 1446817-84-0 |
| Name | ABX-1431 |
| Molecular Formula | C20H22F9N3O2 |
| Molecular Weight | 507.39 |
| Solubility | Soluble in DMSO ≥10mg/mL;Soluble in Water ＜ 1mg/mL |
| Purity | ≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD31735112 |
| SMILES | O=C(N1CCN(CC2=CC=C(C(F)(F)F)C=C2N3CCCC3)CC1)OC(C(F)(F)F)C(F)(F)F |
| Target Point | MGLL (serine hydrolase monoacylglycerol lipase) |
| Passage | Metabolic Enzyme&Protease |
| Background | ABX-1431 is a highly potent, selective, covalent, irreversible MGLL (serine hydrolase monoacylglycerol lipase) inhibitor |
| Biological Activity | ABX-1431是一种有效的、选择性、能穿透中枢神经系统的单酰基甘油脂酶(MGLL)抑制剂，对人源MGLL和鼠源MGLL的IC50值分别为14 nM和27 nM。[1-2] |
| Data Literature Source | [1] Cisar JS，et al. J Med Chem. 2018，61(20):9062-9084. [2] Ming Jiang，et al. J Med Chem. 2018，61(20): 9059–9061. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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