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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > Methylene Blue TrihydrateeCAS：7220-79-3
Molecular Formula：C16H18ClN3S·3H2O
Molecular Weight：373.9
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light brown to black Solid
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| CAS | 7220-79-3 |
| Name | Methylene Blue Trihydratee |
| Molecular Formula | C16H18ClN3S·3H2O |
| Molecular Weight | 373.9 |
| Solubility | Soluble in Water |
| Purity | ≥98% |
| Appearance | Light brown to black Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-515-2 |
| MDL | MFCD00150008 |
| SMILES | CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.O.O.O.[Cl-] |
| Target Point | Guanylate Cyclase;NO Synthase;Monoamine Oxidase |
| Passage | Metabolic&Enzyme;Neuronal Signaling |
| Background | Methylene Blue Trihydratee is a guanylate cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. |
| Biological Activity | Methylene blue trihydrate (C.I. Basic Blue 9 trihydrate) 是一种鸟苷酸环化酶 (sGC)，单胺氧化酶 A (MAO-A) 和 NO 合酶 (NOS) 抑制剂。Methylene blue trihydrate 是一种血管加压药，在医疗中通常用作染料。Methylene blue trihydrate 具有抗伤害感受，抗疟疾，抗抑郁和抗焦虑作用，可用于高铁血红蛋白血症，神经退行性疾病和异环磷酰胺引起的脑病的研究。[1-3] |
| Data Literature Source | [1]. Delport A，et al. Methylene blue and its analogues as antidepressant compounds. Metab Brain Dis. 2017 Oct;32(5):1357-1382. [2]. Masaki E，et al. Methylene blue，a soluble guanylyl cyclase inhibitor，reduces the sevoflurane minimum alveolar anesthetic concentration and decreases the brain cyclic guanosine monophosphate content in rats. Anesth Analg. 1999 Aug;89(2):484-9. [3]. McCartney SL，et al. Intraoperative vasoplegia: methylene blue to the rescue! Curr Opin Anaesthesiol. 2018 Feb;31(1):43-49 |
| Unit | Bottle |
| Specification | 200mg 500mg 1g |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
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Bioinspired design of underwater superoleophobic Poly(N-isopropylacrylamide)/ polyacrylonitrile/TiO2 nanofibrous membranes for highly efficient oil/water separation and photocatalysis
Click to check >>Author：Sun F; Ren HT; Li TT; Huang SY; Zhang Y; Lou CW; L
IF：6.2750
Publish_to：Environ Res
PMID：32302872
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