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SKU	Tongzhou Beijing	Haidian Beijing	Wuhan	Guangzhou
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English Name	Anti-CNOT2 Polyclonal Antibody
Chinese Name	细胞表面趋化因子受体4相关蛋白2抗体
Host	Rabbit
Clone Type	Polyclonal Antibody
Subtype	IgG
Dilution Ratio	WB 1:1000-3000. IHC 1:50-200.
Target	CNOT2
Synonyms	CCR4 associated factor 2; CCR4 NOT transcription complex subunit 2; CCR4-associated factor 2; CCR4-NOT transcription complex subunit 2; CDC36; CNOT2; CNOT2_HUMAN; HSPC131; MSTP046; Negative regulator of transcription 2; NOT2 (negative regulator of transcription 2 yeast) homolog; NOT2; NOT2H;
Background	Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specifically involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of embryonic stem (ES) cell identity.
Swiss Prot	Q9NZN8
Gene ID	4848
Subcellular Location	Cytoplasm Nucleus
Immunogen	A synthetic peptide of human CNOT2
Public Immunogen Range	380-430/540aa
Calculated MW	22/41/52/54/60kDa
Purification Method	Affinity purification
Storage Buffer	PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
Storage	Store at -20℃. Avoid freeze/thaw cycles.
Unit	Piece
Specification	50ul 100ul
Reactivity	Human Mouse
Application	WB IHC