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SKU	Tongzhou Beijing	Haidian Beijing	Wuhan	Guangzhou
K110463P-50ul	Inquiry	Inquiry	Inquiry	Inquiry
K110463P-100ul	Inquiry	Inquiry	Inquiry	Inquiry

English Name	Anti-EPHB4 Polyclonal Antibody
Chinese Name	酪氨酸蛋白激酶受体B4抗体
Host	Rabbit
Clone Type	Polyclonal Antibody
Subtype	IgG
Dilution Ratio	IHC 1:50-200.
Target	EPHB4
Synonyms	Ephb4; EPHB4_HUMAN; Ephrin receptor EphB4; Ephrin type-B receptor 4; Hepatoma Transmembrane Kinase; HTK; MYK 1; MYK1; TYRO 11; TYRO11; Tyrosine-protein kinase receptor HTK; Tyrosine-protein kinase TYRO11;
Background	Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 it is involved in the regulation of cell adhesion and migration, and plays a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells.
Swiss Prot	P54760
Gene ID	2050
Subcellular Location	Cell membrane Cytoplasm
Immunogen	A synthetic peptide of human EPHB4
Public Immunogen Range	880-930/987aa
Calculated MW	33/45/56/108kDa
Purification Method	Affinity purification
Storage Buffer	PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
Storage	Store at -20℃. Avoid freeze/thaw cycles.
Unit	Piece
Specification	50ul 100ul
Reactivity	Human Mouse
Application	IHC