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SKU	Tongzhou Beijing	Haidian Beijing	Wuhan	Guangzhou
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K110465P-100ul	Inquiry	Inquiry	Inquiry	Inquiry

English Name	Anti-CD46 Polyclonal Antibody
Chinese Name	膜辅蛋白抗体
Host	Rabbit
Clone Type	Polyclonal Antibody
Subtype	IgG
Predicted Reactivity	Chimpanzee;Chlorocebus aethiops;Cavia porcellus
Dilution Ratio	IHC 1:100-300.
Target	CD46
Synonyms	AHUS2; Antigen defined by monoclonal antibody TRA 2 10; Antigen identified by monoclonal antibody TRA 2 10; CD46; CD46 antigen; CD46 antigen complement regulatory protein; CD46 molecule; CD46 molecule complement regulatory protein; Complement membrane cofactor protein; MCP; MCP_HUMAN; Measles virus receptor; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); Membrane cofactor protein; MGC26544; MIC10; TLX; TRA2.10; Trophoblast leucocyte common antigen; Trophoblast leukocyte common antigen; Trophoblast lymphocyte cross reactive antigen;
Background	The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
Swiss Prot	P15529
Gene ID	4179
Subcellular Location	Cell membrane
Immunogen	A synthetic peptide of human CD46
Public Immunogen Range	35-85/392aa
Calculated MW	37/39/40/41/42/43/44kDa
Purification Method	Affinity purification
Storage Buffer	PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
Storage	Store at -20℃. Avoid freeze/thaw cycles.
Unit	Piece
Specification	50ul 100ul
Reactivity	Human
Application	IHC