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Anti-GNL3L Polyclonal Antibody

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Cat.No：K110672P Solarbio

Reactivity：Human,Mouse

Application： IHC

Storage：Store at -20℃. Avoid freeze/thaw cycles.

Host：Rabbit

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Product Information

Name	Anti-GNL3L Polyclonal Antibody
Host	Rabbit
Clone Type	Polyclonal Antibody
Subtype	IgG
Predicted Reactivity	Cow
Dilution Ratio	IHC 1:50-200.
Target	GNL3L
Background	Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.
Swiss Prot	Q9NVN8
Gene ID	54552
Subcellular Location	Nucleus Cytoplasm
Immunogen	A synthetic peptide of human GNL3L
Public Immunogen Range	1-51/582aa
Calculated MW	66kDa
Purification Method	Affinity purification
Storage Buffer	PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
Storage	Store at -20℃. Avoid freeze/thaw cycles.
Piece	Piece
Specification	50ul 100ul
Reactivity	Human Mouse
Application	IHC

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Kindly reminder：Quick spin before use. If you have any questions, please contact us.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.