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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > 1-Methyl-D-TryptophanCAS：110117-83-4
Molecular Formula：C12H14N2O2
Molecular Weight：218.25
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 110117-83-4 |
| Name | 1-Methyl-D-Tryptophan |
| Molecular Formula | C12H14N2O2 |
| Molecular Weight | 218.25 |
| Solubility | Soluble in Water ≥1mg/mL(Need to add HCl dropwise to help dissolve) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00274271 |
| SMILES | N[C@H](CC1=CN(C)C2=CC=CC=C12)C(O)=O |
| Target Point | Indoleamine 2,3-Dioxygenase (IDO) |
| Passage | Immunology & Inflammation;Metabolic Enzyme&Protease |
| Background | 1-Methyl-D-Tryptophan is an inhibitor of the indoleamine 2,3-dioxygenase (IDO) pathway. |
| Biological Activity | Indoximod (D-1MT, NLG8189)是吲哚胺2,3-双加氧酶 (IDO) 通路抑制剂，Ki 为19 μM。[1] |
| IC50 | IDO:19μM(Ki) |
| Data Literature Source | [1]. Hou DY，et al. Inhibition of indoleamine 2，3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophancorrelates with antitumor responses. Cancer Res. 2007 Jan 15;67(2):792-801. |
| Unit | Bottle |
| Specification | 200mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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