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My CartCAS：188062-50-2
Molecular Formula：C28H36N12O2·H2SO4
Molecular Weight：670.74
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 188062-50-2 |
| Name | Abacavir Sulfate |
| Molecular Formula | C28H36N12O2·H2SO4 |
| Molecular Weight | 670.74 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 620-488-4 |
| MDL | MFCD04112763 |
| SMILES | NC1=NC(NC2CC2)=C3N=CN([C@H]4C=C[C@@H](CO)C4)C3=N1.O=S(O)(O)=O.NC5=NC(NC6CC6)=C7N=CN([C@H]8C=C[C@@H](CO)C8)C7=N5 |
| Target Point | Reverse Transcriptase |
| Passage | Anti-infection |
| Background | It is a nucleoside analog reverse transcriptase inhibitor (NRTI), which can be used for HIV and AIDS related research. |
| Biological Activity | Abacavir is a nucleoside reverse transcriptase inhibitor marketed the treatment of infection with the human immunodeficiency virus type 1 (HIV). [1] Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside analogue. It is metabolised intracellularly to a 2'-deoxyguanosine nucleoside analogue which competitively inhibits HIV reverse transcriptase and terminates proviral DNA chain extension. [2] |
| Data Literature Source | [1]. Charneira C，et al. Reactive aldehyde metabolites from the anti-HIV drug abacavir: amino acid adducts as possible factors in abacavir toxicity. Chem Res Toxicol. 2011 Dec 19;24(12):2129-41. [2]. Hervey PS，et al. Abacavir: a review of its clinical potential in patients with HIV infection. Drugs. 2000 Aug;60(2):447-79. |
| Unit | Bottle |
| Specification | 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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