Gene Name |
B4GALT3 |
English Name |
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 |
Chinese Name |
β-1,4-半乳糖基转移酶3 |
Uniprot |
O60512 |
GeneID |
8703 |
Predicted Cross Reactivity |
Human Mouse Rat (Bovine Gorilla) |
氨基酸大小 |
41kDa |
表达氨基酸 |
20-393aa |
Background |
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes.They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl.Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures.As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor.By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7.This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains.Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. |
Application |
Immunology research |
Source |
E.coli |
Purification |
NI-NTA affinity purification |
Formulation |
Lyophilized from a 0.2 μm filtered solution of Urea, Tris-HCl, PH8.0. |
Delivery Condition |
The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage |
Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
Reconstitution |
Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Purity |
Purity≥85% as determined by reducing SDS-PAGE. |
Endotoxin |
/ |
Bioactive |
Not tested. |
Tag information |
With a 6His tag at the N-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |