Gene Name |
RPLP1 |
English Name |
ribosomal protein, large, P1 |
Chinese Name |
核糖体磷酸蛋白P1 |
Uniprot |
P05386 |
GeneID |
6176 |
Predicted Cross Reactivity |
Human Mouse Rat (Bovine Chicken Pig) |
氨基酸大小 |
13kDa |
表达氨基酸 |
1-114aa |
Background |
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit.The protein, which is a functional equivalent of the E.coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins.It plays an important role in the elongation step of protein synthesis.Unlike most ribosomal proteins, which are basic, the encoded protein is acidic.Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P2.The P1 protein can interact with P0 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer.The protein is located in the cytoplasm.Two alternatively spliced transcript variants that encode different proteins have been observed.As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. |
Application |
Immunology research |
Source |
E.coli |
Purification |
NI-NTA affinity purification |
Formulation |
Lyophilized from a 0.2 μm filtered solution of Urea, Tris-HCl, PH8.0. |
Delivery Condition |
The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage |
Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
Reconstitution |
Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Purity |
Purity≥85% as determined by reducing SDS-PAGE. |
Endotoxin |
/ |
Bioactive |
Not tested. |
Tag information |
With a 6His tag at the N-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |