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My CartCAS：521-74-4
Molecular Formula：C9H5Br2NO
Molecular Weight：302.95
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Yellow to brown Solid
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| CAS | 521-74-4 |
| Name | Broxyquinoline |
| Molecular Formula | C9H5Br2NO |
| Molecular Weight | 302.95 |
| Solubility | Soluble in DMSO ≥1mg/mL;Soluble in Water ＜ 0.1mg/mL |
| Purity | ≥98% |
| Appearance | Yellow to brown Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 208-317-8 |
| MDL | MFCD00006785 |
| SMILES | OC1=C2N=CC=CC2=C(Br)C=C1Br |
| InChIKey | ZDASUJMDVPTNTF-UHFFFAOYSA-N |
| InChI | InChI=1S/C9H5Br2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H |
| PubChem CID | 2453 |
| Target Point | Parasite |
| Passage | Anti-infection |
| Background | Broxyquinoline is an antiprotozoal compound. |
| Biological Activity | Broxyquinoline (Dibromohydroxyquinoline) is a potent severe fever with thrombocytopenia syndrome virus (SFTSV) inhibitor with an IC50 of 5.8 μM. Broxyquinoline is an antiprotozoal agent[1-2]. |
| Data Literature Source | [1]. Shuofeng Yuan，et al. Screening of an FDA-Approved Drug Library with a Two-Tier System Identifies an Entry Inhibitor of Severe Fever with Thrombocytopenia Syndrome Virus. Viruses. 2019 Apr 25;11(4):385. [2]. Fritzler JM，et al. Novel anti-Cryptosporidium activity of known drugs identified by high-throughput screening against parasite fatty acyl-CoA binding protein (ACBP). J Antimicrob Chemother. 2012 Mar;67(3):609-17. |
| Unit | Bottle |
| Specification | 100mg 250mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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