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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > GPCR & G Protein > FamotidineCAS：76824-35-6
Molecular Formula：C8H15N7O2S3
Molecular Weight：337.45
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 76824-35-6 |
| Name | Famotidine |
| Molecular Formula | C8H15N7O2S3 |
| Molecular Weight | 337.45 |
| Solubility | Soluble in DMSO ≥10mg/mL;Soluble in Water ＜ 1mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 616-396-9 |
| MDL | MFCD00079297 |
| SMILES | N=C(NS(=O)(N)=O)CCSCC1=CSC(NC(N)=N)=N1 |
| Target Point | Histamine Receptor |
| Passage | GPCR & G Protein;Neuronal Signaling;Immunology & Inflammation |
| Background | It is a histamine H2 receptor antagonist. |
| Biological Activity | Famotidine (MK-208) is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion. |
| IC50 | Histamine H2 Receptor[1]. |
| Data Literature Source | [1]. Inan，A.，et al.，Effects of the histamine H2 receptor antagonist famotidine on the healing of colonic anastomosis in rats. Clinics (Sao Paulo)，2009. 64(6): p. 567-70. [2]. Miyata，K.，et al.，Studies on the mechanism for the gastric mucosal protection by famotidine in rats. Jpn J Pharmacol，1991. 55(2): p. 211-22. |
| Unit | Bottle |
| Specification | 500mg 1g |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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