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Alzheimer's disease small molecule compound Kit-1

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Alzheimer's disease small molecule compound Kit-1
Cat.No:
IK-AD-1
Brand:
Solarbio
CAS号产品货号产品名称分子式分子量对应靶点产品描述
22427-39-0IG0240Ginsenoside Rg1;人参皂苷Rg1C42H72O14801.01Amyloid-β通过降低大脑Aβ水平来发挥作用。
52286-59-6IG0650Ginsenoside Re;人参皂苷ReC48H82O18947.15Amyloid-βGinsenoside Re可降低β-淀粉样蛋白(Aβ),抑制 JNK和NF-κB。
80418-24-2IN0240Notoginsenoside R1;三七皂苷R1C47H80O18933.13Amyloid-β;TNF-α是三七中的主要生物活性成分,据报道具有一定的神经元保护作用。通过上抑制Aβ积累对阿尔茨海默病 APP/PS1小鼠模型具有保护作用。
20736-08-7IS0520Saikosaponin C;柴胡皂苷CC48H78O17927.12Amyloid-β;tau protein是柴胡中的活性成分,在阿尔滋海默症中主要靶作用于amyloid beta和tau蛋白。
134308-13-7IT2230Tolcapone;托卡朋C14H11NO5273.24Aβ42是一种Aβ42寡聚和原纤维形成的有效抑制剂
97657-92-6IL0790Latrepirdine 2HClC21H25N3·2HCl392.37Amyloid-β刺激淀粉样前体蛋白 (APP) 分解代谢和β-淀粉样蛋白(amyloid-β,Aβ)分泌。
425386-60-3IS1540Semagacestat;司马西特C19H27N3O4361.44Amyloid β;γ-secretase是一种 γ-secretase 抑制剂,抑制β-amyloid (Aβ42),Aβ38和Aβ40。可用于阿尔茨海默病的相关研究。
58749-23-8IL2000Licochalcone B;甘草查尔酮 BC16H14O5286.28Amyloid β抑制淀粉样蛋白β(amyloid β;Aβ420)自聚集作用并分解预先形成的Aβ42原纤维,通过螯合金属离子减少金属诱导的Aβ42聚集。

本套装精选了数种靶向Amyloid-β的化合物,可用于阿兹海默症的相关研究,便于客户进行初筛等操作。客户也可根据自己的需求灵活定制专属Kit。
1. 具有良好的生物活性,且为小包装规格,可用于初筛、预实验、初步验证等操作
2. 靶向Amyloid-β等受体 
3. 可用于探索阿尔茨海默病的相关研究,例如分子机制、病理活动等
4. 客户可根据自己的实验需求灵活定制Kit:规格、套装组成、产品种类、数量、形式(溶液/干粉)均可定制。

Remark:
These protocols are for reference only. Solarbio does not independently validate these methods.

Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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