Alogliptin
Cat.No:IA3180 Solarbio
CAS:850649-61-5
Molecular Formula:C18H21N5O2
Molecular Weight:339.39
Storage:Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:White to off-white Solid
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Metabolic Enzyme & Protease >
AlogliptinCAS:850649-61-5
Molecular Formula:C18H21N5O2
Molecular Weight:339.39
Storage:Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:White to off-white Solid
Qty:
Size:
CAS | 850649-61-5 |
Name | Alogliptin |
Molecular Formula | C18H21N5O2 |
Molecular Weight | 339.39 |
Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
Purity | ≥98% |
Appearance | White to off-white Solid |
Storage | Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
EC | EINECS 821-899-3 |
MDL | MFCD09833196 |
SMILES | O=C(C=C(N1C[C@H](N)CCC1)N(C2=O)CC3=C(C#N)C=CC=C3)N2C |
Target Point | Dipeptidyl Peptidase(DPP-4) |
Passage | Metabolic Enzyme&Protease |
Background | It is a highly active DPP4 selective inhibitor. |
Biological Activity | Alogliptin (SYR-322) is a potent, selective inhibitor of the serine protease dipeptidyl peptidase IV (DPP-4) with IC50 values of 2.63 nM and exhibits greater than 10,000 fold selectivity over the closely related serine proteases DPP-8 and DPP-9.[1-4] |
Data Literature Source | [1] Huan Y,et al.J Pharmacol Toxicol Methods. 2015;71:8-12. [2] Feng J,et al.J Med Chem. 2007,17;50(10):2297-300. [3] Lee B,et al.Eur J Pharmacol. 2008,28;589(1-3):306-14. |
Unit | Bottle |
Specification | 5mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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