Anti-IPO4 Polyclonal Antibody
Cat.No:K110952P Solarbio
Reactivity:Human,Mouse
Application: WB,IHC
Storage:Store at -20℃. Avoid freeze/thaw cycles.
Host:Rabbit
Qty:
Size:
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My CartReactivity:Human,Mouse
Application: WB,IHC
Storage:Store at -20℃. Avoid freeze/thaw cycles.
Host:Rabbit
Qty:
Size:
Name | Anti-IPO4 Polyclonal Antibody |
Host | Rabbit |
Clone Type | Polyclonal Antibody |
Subtype | IgG |
Dilution Ratio | WB 1:1000-3000. IHC 1:50-200. |
Target | IPO4 |
Background | Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. |
Swiss Prot | Q8TEX9 |
Gene ID | 79711 |
Subcellular Location | Cytoplasm Nucleus |
Immunogen | Recombinant protein of human IPO4 |
Public Immunogen Range | 1-350aa |
Calculated MW | 119kDa |
Purification Method | Affinity purification |
Storage Buffer | PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
Storage | Store at -20℃. Avoid freeze/thaw cycles. |
Piece | Piece |
Specification | 50ul 100ul |
Reactivity | Human Mouse |
Application | WB IHC |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder:Quick spin before use. If you have any questions, please contact us.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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